ADH pathway in circulatory system

The antidiuretic hormone (ADH) is produced by the pituitary gland, and its target organ is the kidney. ADH leaves the head in the jugular vein.
In what order will the hormone pass through the following blood vessels to reach its target?

A. Vena Cava → Aorta → Pulmonary Vein → Renal Artery → Pulmonary Artery

B. Pulmonary Vein → Vena Cava → Aorta-> Pulmonary Artery → Renal Artery

C. Vena Cava → Pulmonary Artery → Pulmonary Vein → Renal Artery → Aorta

D. Vena Cava → Aorta → Pulmonary Vein → Pulmonary Artery → Renal Artery

E. Vena Cava → Pulmonary Artery → Pulmonary Vein → Aorta → Renal Artery

The correct answer is C. Can someone tell me why it is not D?

Hi! So we know that the hormone leaves through the VEIN so it has to enter the heart and lungs before reaching the kidneys. Remember the vessel carrying the deoxygenated blood to the lungs is the ARTERY and the one to the heart with the oxygenated blood is the VEIN. So first it enters the heart through the vena cava from the jugular vein - it passes through the right side of the heart and enters the lungs through the pulmonary artery and moves towards the left side of the heart through the pulmonary vein.

However I believe the answer should be E as it passes from the heart through the aorta and then to the renal artery where ADH finally enters the kidney.

Someone correct me on that if I’m wrong! Hope this helps:))


I also think that the answer of this question is E