MITOSIS AND MEIOSIS
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The spindle is a microtubule-based scaffold that ensures even chromosome distribution between daughter cells
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Crossing over is the process that produces new and random combinations of genes through their exchange between 2 non-sister chromatids of homologous chromosomes. It happens during meiosis, and more precisely, during prophase.
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Chromatin is the general packaging of DNA around histone proteins
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Histone + protein = nucleosome helps condense DNA to fit within the cell’s nucleus
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During metaphase, the nuclear membrane is completely disintegrated. The chromosomes align in the middle of the cell, to prepare for chromatid separation
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Anaphase is the phase where the centromeres are split. Each half moves to opposite poles
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At the beginning of mitosis, a chromosome consists of two sister chromatids
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Chromatids are used to describe the chromosome in its duplicated form
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Prophase is the first phase of mitosis. It is the phase during which the the nuclear membrane begins to disintegrate
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Throughout most of the cell cycle, DNA is packaged in the form of chromatin
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Telophase is the phase where the nuclear envelope reforms around the separated chromosomes
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Centrioles are made of microtubules (a polymer of tubulin) and form the aster and spindle: they are fibers of microtubules that will split centromeres
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The centromere is the area where the 2 sister chromatids of a chromosome are in contact
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Chromatin exists in an organization known as a chromosome during mitosis and meiosis
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Chromatids are used to describe the chromosome in its duplicated form
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What are the different phases of mitosis?
- prophase
- metaphase
- anaphase
- telophase
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Prophase is precedented by genetic replication during interphase
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What is the number of chromosomes during metaphase? 46
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What is the number of chromatids during telophase? 92
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What is the number of chromatids and chromosomes at the end of mitosis? 46 and 46
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A tetrad is 2 attached homologous chromosomes (4 chromatids)
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What is the number of chromatids during telophase II of meiosis? 46