EXplanation of protein structure , imat 2018 question 24

Hi guys I can’t seem to answer these type of actions can someone please explain how to know the level of structure of a protein.

The enzyme HIV-1 protease is produced by the HIV virus.

The enzyme is formed from two identical chains of 99 amino acids. In each chain, amino acids 25, 26 and 27 in the sequence form part of the active site.

Which levels of structure control the shape of the active site of the HIV protease?

A. primary, secondary and tertiary only
B. primary, secondary, tertiary and quaternary.
C. primary and quaternary only
D. secondary and tertiary only
E. quaternary only

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Hi!

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I think the answer is B. Because the key word in the question’’ is two identical chains of 99 amino acids’ . Meaning that it must have a quaternary structure by definition.

We know for sure that it has a tertiary structure as it’s an enzyme but it also has a quaternary structure because it has e amino acid chains

so all enzymes have a Tertiary protein structure ?

I think so as they are 3D molecules. The tertiary structure gives rise to a 3D Shape. Quaternary is a more complex 3D shape hence they must have at least 2 polypeptide chains.

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eg: haemoglobin (4 coiled structures)

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