Homologous pairs

Hey!
We know that the synaptonemal complex causes the homologous pairs bound together tighty…
Does the cohsion proteins at the centromere play a role in this binding?

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Hi!
yes, I think cohesion proteins plays a crucial role. Early in prophase I, homologous chromosomes come together to form a synapse and they are tightly bound in perfect alignment by a protein lattice called a synaptonemal complex and by cohesion proteins at the centromere which dissolves completely during metaphase to ensure the seperation of the sister chromatids.
Hope it helps!
Please help, If anyone has a better explanation.

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Hey!
That’s exactly what I have read before asking this question😀
So maybe we can say that in mitosis and meiosis1 and 2 centromere separation occures…

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hi!
I think we can say that just for mitosis and meiosis II as in meiosis one centromere do not separate rather homologous chromosomes separate and there’s no change in chromosome no.
although we can say that the cohesion protein dissolves in meiosis I.

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