IMAT 2016 Q33 [Hydrolysed Dipeptide]

The dipeptide represented below is in aqueous solution.


Which numbered bond (1 to 5) needs to be broken (hydrolysed) in this dipeptide to directly form two amino acids?

A. 1
B. 5
C. 3
D. 4
E. 2

The correct answer is C.

Amino-acids are organic compounds that are composed of 2 distinct groups : one is invariant, and the other one, called the R-group, is specific to each amino acid. The invariant group, common to all amino acids, is made of 2 functional groups :

  • Amino or -NH2

  • Carboxyl or -COOH

They are both attached to an atom of carbon, that we will call CĪ± ; that same atom is linked to a single atom of hydrogen and the R-group.

To answer this question, you have to be able to identify the amino and carboxyl functional groups on the molecule.

Once you get that, you can determine that you have to break the bond between N and C at the ā€œ3ā€ position to form 2 amino acids, like the following :


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