Membrane soluble hormones

Practice Question Solving
1

good morningg!
do we need to know the details of which hormones are soluble or not?
I only know that steroids can pass and Amino acid derivatives like epinephrine cannot
are there any specific hormones that break the rule that I need to know about?

2

Hormones such as estrogen, testosterone, progesterone, aldosterone, and those produced in the thyroid are fat-soluble and repel water (hydrophobic), they need special carriers. Just remember steroid hormones AND thyroid hormone are lipid soluble. Darius also mentioned anything ending with “ol” are water soluble. All other amino acid–derived hormones are water soluble. Epinephrine is very small (adrenal) so it is water soluble by the way, so is norepinephrine dopamine, glucagon, and ADH.

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3

thank you! that is good to remember will memorize them now

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4

I agree, but those ending with “-ol” are alcohols, so they are water-soluble, but not lipid soluble:) ex. cortisol

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5

I just edited it to correct it :))

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6

i thought AA are not lipid soluble, but in this case is this mean they all can pass or not?

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7

Some amino acid derivative hormones (such as adrenaline) are very polar and cannot pass the cell membrane of target cells = launch a secondary messenger cAMP.

Others as thyroid hormones are non-polar so they can pass through the cell membrane in the target cell.

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