Renal failure and electrolyte management

Kidney disease is one of the leading causes of hospital admissions and data indicate that renal
failure rates are rising steadily. In addition to profound effects on electrolyte management and the
disposal of metabolic waste products, which process does renal failure compromise?

A)Oxygen carriage in the bloodstream
B) Myocardial contractility
C) Cognition
D) Pulmonary gas exchange
E)All of the above

The correct answer is A. Can someone please explain me the mechanism?

The kidneys manufacture a hormone called erythropoietin, which tells the bone marrow to make more red blood cells. so, in a case if our kidneys are damaged our erythropoietin levels can fall and our body will not make enough RBC’s thus affecting oxygen carriage as around 97% of oxygen in our bloodstream are carried in the form of oxyhemoglobin.
Hope it helps:)


Hi! i agree with Ujjwal,

non functional kidneys would mean no more erythropoietin secretion so we would have a lower RBC count in blood, thus lower oxygen carriage
i guess B) C) D) would be a consequence of A), not a direct consequence of renal failure


Thank you both :heart:
I forgot to consider about erythropoietin